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Dr Matt Neale

Meiotic DSB Patterning: A multifaceted process
Cell Cycle 2016, Jan 5. doi: 10.1080/15384101.2015.1093709

Tel1(ATM)-mediated interference suppresses clustered meiotic double-strand-break formation.
Nature 2015, Jan 5. doi: 10.1038/nature13993

Homeostatic regulation of meiotic DSB formation by ATM/ATR.
Experimental Cell Research 2014, 329 (1). pp. 124-131. ISSN 1090-2422

DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities.
Mol Cell 2013, Dec 3;53(1):7-18.

Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase mec1(ATR).
Open Biol 2013;3(7):130019.

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1.
Nature 2011; 144(5): 719-731.

A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation.
Cell 2011; 144(5): 719-731.

PRDM9 points the zinc finger at meiotic recombination hotspots.
Genome Biology 2010; 11: 104.

Evidence that MEK1 positively promotes interhomologue double-strand break repair.
Nucleic Acids Research 2010; 38(13): 4349-4360.

Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.
Molecular Cell 2009; 33(1):117-123

End-labelling and Analysis of Spo11-Oligonucleotide Complexes in Saccharomyces cerevisiae.
Methods in Molecular Biology 2009; 557:183-195.

Excess single-stranded DNA inhibits meiotic double-strand break repair.
PLoS Genet 2007; 3(11): e223 doi:10.1371/journal.pgen.0030223

Interactions between Mei4, Rec114, and other proteins required for meiotic DNA double-strand break formation in Saccharomyces cerevisiae.
Chromosoma 2007; 116(5): 471-86.

Clarifying the mechanics of DNA strand exchange in meiotic recombination.
Nature 2006; 442(7099): 153-8.

Initiation of meiotic recombination by formation of DNA double-strand breaks: Mechanism and regulation.
Biochem Soc Trans. 2006; 34(Pt 4): 523-5.

Endonucleolytic processing of covalent protein-linked DNA double-strand breaks.
Nature 2005; 436(7053): 1053-7.

Wild-type levels of Spo11-induced DSBs are required for normal single-strand resection during meiosis
Molecular Cell 2002; 9(4): 835-46.

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